Expression of Cytolytic Lymphocyte-Associated Antigens in Pulmonary Lymphomatoid Granulomatosis
نویسندگان
چکیده
منابع مشابه
Expression of cytolytic lymphocyte-associated antigens in pulmonary lymphomatoid granulomatosis.
Paraffin-embedded lung wedge biopsy specimens from 14 patients with pulmonary lymphomatoid granulomatosis (LYG) were analyzed using immunoperoxidase stains specific for T cell- and natural killer cell-associated antigens. Nine cases had a minor population of CD20+ large B-cells (B-cell LYG) amidst a background of CD3- and betaF1-immunoreactive T cells. In 8 of the 9 B-cell LYG cases, the majori...
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Lymphomatoid granulomatosis (LYG) of the lung is an extremely rare, Epstein-Barr virus-related lymphoproliferative disease. We report a case of pulmonary LYG that presented as a large necrotic mass.
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A case of lymphomatoid granulomatosis is presented demonstrating the most common chest radiograph findings as well as some infrequent but recognized associations. The clinical presentation and pathogenesis are discussed. The difficulty in radiological diagnosis is highlighted.
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RATIONALE Lymphomatoid granulomatosis is a very rare Epstein-Barr virus-driven lymphoproliferative disease. This disease has high mortality owing to its low incidence in conjunction with nonspecific presentations, which contribute to delays in diagnosis. PATIENT An 87-year-old male had a week-long history of intermittent fever and general weakness. A chest radiograph showed multifocal patchy ...
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A 70-year-old female presented with a 4-week history of dry cough and wheezing. Chest radiograph showed a 10.5 cm mass-like density in the anterior mediastinum which had not been previously visualized. Computed tomography scan (CT) of the chest showed a right hilar mass encasing and narrowing right upper lobe bronchus and right mainstem bronchus and secondary atelectatic changes. Biopsy was con...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2002
ISSN: 0002-9173,1943-7722
DOI: 10.1309/pmr7-7xly-f10u-4v1q